Trial summary
This study is testing whether wearing compression garments—surgical gloves and compression stockings—can help reduce nerve damage (neuropathy) in patients receiving oxaliplatin chemotherapy for gastrointestinal cancers. The aim is to determine if patients can safely tolerate the compression garments and if wearing the garments can help reduce nerve damage (neuropathy) in patients receiving oxaliplatin chemotherapy for gastrointestinal cancers.
The study is non-randomised, which means patients are not randomly assigned to groups. All participants will receive the compression therapy while having their oxaliplatin-based chemotherapy.
The goal is to see if this simple method can safely and effectively manage one of the common side effects of oxaliplatin- peripheral neuropathy.
Participants will wear compression gloves (two surgical gloves per hand) and lower-limb compression stockings beginning 30 minutes before, during, and for 30 minutes after each oxaliplatin infusion. Oxaliplatin is typically administered every 2–3 weeks, depending on the chemotherapy regimen. The compression intervention will be used for a minimum of 12 weeks of treatment (approximately four to six cycles), unless oxaliplatin is discontinued earlier. Follow-ups will occur 12 and 24 weeks after end of oxaliplatin treatment.
Trial details
Short title
COMPRES
Diagnosis
Gastric / gastroesophageal cancer
Colorectal cancer
Type of treatment
Medical Oncology
Phase
I
Locations
Who can participate
Clinical trials can have restrictive criteria of who can and can’t participate, talk to your healthcare provider if you are interested in this clinical trial.