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Oesophageal Cancer

Oesophageal cancer occurs when uncontrolled abnormal cells develop in layers of the oesophageal wall.

Jump to: Quick facts Types of oesophageal cancer Signs and symptoms Stages Treatment FAQs

Quick facts about oesophageal cancer

  • The oesophagus is the tube that transports food from your throat to your stomach to be digested. There are three layers of the oesophageal wall, which include the mucosa (made up of squamous cells), submucosa and muscle layer (muscularis propria), in addition to the outer covering (adventitia)

  • Most oesophageal cancers begin in the lower section of the oesophagus

  • Each year more than 1,600 people in Australia are diagnosed with oesophageal cancer

  • Oesophageal cancer is the 14th most common cancer in Australian men and is more common in people over the age of 60

Types of oesophageal cancer

The two most common types of oesophageal cancer are:

  • Oesophageal adenocarcinoma

    Cancer that develops in the glandular cells which line the oesophagus. This type of cancer typically forms in the lower section of the oesophagus.

  • Oesophageal squamous cell carcinoma

    Cancer that begins in squamous cells that line the oesophagus. This often develops in the middle and upper part of the oesophagus.

Other types of oesophageal cancer include small cell carcinoma, lymphoma, neuroendocrine tumours and gastrointestinal stromal tumours.

Signs and symptoms of oesophageal cancer

As signs and symptoms for oesophageal cancer can be similar to other common conditions, it’s important to see your GP or healthcare professional if you experience any of the symptoms below. Discussing anything concerning with your doctor as soon as possible can help give you peace of mind and offer the best chance of successful treatment if you receive an oesophageal cancer diagnosis.

Oesophageal cancer can be difficult to detect as there are often no symptoms during the early stages. However, as the disease progresses symptoms may include:

Pain or difficulty swallowing such as a feeling of choking when swallowing

Heartburn

Vomiting blood

Black or bloody stools

Unexplained fatigue

Discomfort in the upper abdomen particularly when eating

Weight loss

Coughing or hoarseness

Stages of oesophageal cancer

The TNM system is used to stage oesophageal cancer, and it helps doctors understand what your cancer looks like. The TNM stands for:

  • Tumour – The extent to which the tumour infiltrates into surrounding tissue

  • Node – Is a measure of surrounding lymph nodes involvement

  • Metastasis – Describes whether or not the cancer has spread to other parts of the body

The TNM information, along with other tests, helps determine the stage of your oesophageal cancer using the guidelines below:

  • Stage 0

    The cancer is only in the top layer of the oesophageal lining (epithelium) and has not spread to deeper layers of the oesophagus.

    Stage 0 oesophageal cancer illustration

  • Stage I

    The cancer has grown into the mucosa, submucosa or muscle layer (muscularis propria).

    Stage I oesophageal cancer illustration

  • Stage II

    The cancer has spread to the muscularis propria or outer layer of the oesophagus (adventitia). Alternatively, the cancer has grown into the mucosa or submucosa and has spread to one or two nearby lymph nodes.

    Stage II oesophageal cancer illustration

  • Stage III

    The cancer has spread to the mucosa, submucosa, adventitia or muscularis propria and no more than six nearby lymph nodes. Alternatively, the cancer has grown into the pleura, pericardium or diaphragm and no more than two nearby lymph nodes.

    Stage III oesophageal cancer illustration

  • Stage IV

    The cancer has spread beyond the oesophageal wall to nearby lymph nodes and parts of the body such as the pleura, pericardium, diaphragm, trachea, aorta and spine, or throughout the body to distant lymph nodes and/or organs such as the liver or lungs.

    Stage IV oesophageal cancer illustration

Treatment for oesophageal cancer

There are many different types of treatment for oesophageal cancer. Your treatment will depend on you and your cancer.

Frequently asked questions about oesophageal cancer

Helpful links

Australasian Gastro-Intestinal Trials Group (AGITG)

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Cancer Council: Understanding stomach and oesophageal cancers

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Cancer Council: What is oesophageal cancer?

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References

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