Your breast cancer may be classified as hormone receptor positive or negative, depending on whether it has particular protein receptors on its surface or not. This is known as the hormone receptor status. Breast cancer cells with hormone receptors may be stimulated by your own natural hormones, or by the pill or hormone replacement therapy.
The hormone receptor status you receive may include:
- ER+ (or ER positive) breast cancer – has receptors for oestrogen
- PR+ (or PR positive) breast cancer – has receptors for progesterone
- ER- and PR- breast cancer – has neither oestrogen or progesterone receptors
If your breast cancer is classified as hormone receptor positive, it may respond to treatments that adjust or block the hormones in the body. This is known as hormone or endocrine therapy.
If your breast cancer is classified as hormone receptor negative, hormone treatment will not be effective.