Myelodysplasia, also known as Myelodysplastic Syndrome (MDS), includes a collection of diseases (sometimes referred to as a group of cancers) which affect the growth and development of healthy blood cells in your bone marrow.1
In the past myelodysplasia was called “pre-leukaemia” as in some cases the disease transforms to Acute Myeloid Leukamia (AML), although this does not always occur.
The malignant cell in myelodysplasia is a myeloid stem cell. Such bone marrow stem cells are cells that can develop into any type of blood cell (i.e. they are responsible for making red blood cells, white blood cells and platelets). 2